Alpha-2-Macroglobulin Injections

Do you know that around 30+ million Americans suffer from arthritic and degenerative conditions? It led to the urge to find concrete solutions to existing problems. Studies found a new biological treatment in joint pain relief known as Alpha 2 Macroglobulin (A2M) human plasma protein, A2MD, CPAMD5, FWP007, and S863-7. A2M is a naturally occurring molecule found in your blood. It is produced by the liver and protects cartilage from proteins known to cause osteoarthritis. A2M molecules are present across the body rather than just concentrated in joints to prevent arthritis.

Patient receiving Alpha-2-Macroglobulin Injections injection to relieve shoulder pain


A2M is a minimally invasive, non-surgical, and innovative procedure shown to:

  • Reduces pain caused by osteoarthritis
  • Improves joint function
  • Prevents the progression of osteoarthritis
  • Decreases pain and inflammation in joints

A2M is safe and effective in helping the following conditions:

  • Osteoarthritis (Knee arthritis, Hip arthritis)
  • Joint injuries (Shoulder, Knee, Elbow, Rotator cuff)
  • Labral Tear
  • Spinal injuries (Neck, Back)
  • Sacroiliac osteoarthritis
  • Sciatica (Lumbar radiculopathy)
  • Herniated disc (Slipped disc, Disc displacement)
  • Degenerative disc disease

How Does it Work?

We thoroughly review your medical history and suggest some examinations to assess your condition. Then create a customized treatment plan after evaluating it. The whole procedure lasts around an hour. It is a minimally invasive procedure where yellow plasma, the concentrated form of A2M, is injected into the affected joint. The patient may experience minimal discomfort for 3-5 days. Patients may begin to experience pain relief in 4-6 weeks. Regular treatments may relieve pain, support tissue growth, or slow or stop the progression of joint degeneration. It may even help prevent or limit the onset of post-traumatic osteoarthritis.

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At Advanced Health & Wellness Center, our Advanced Joint Pain Relief Solutions are very effective at providing pain relief and improving joint functions. Call now to get started with your customized treatment plan!

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